Risk Management



Giant cell arteritis claims are costly and difficult to defend

RONALD W. PELTON, MD, PhD, OMIC Committee Member, and ANNE M. MENKE, RN, PhD, OMIC Risk Manager

A 77-year-old male patient presented for the first time to our insured ophthalmologist to report the sudden onset of intermittent diplopia six days prior and a headache over his eyebrows for one day. Noting right inferior oblique muscle paresis but unable to determine its cause, and with no neuro-ophthalmologist in the region, the eye surgeon referred the patient to a neurologist. The patient told the neurologist that the headache had actually lasted for one month and that he was also experiencing jaw pain. This additional information prompted the neurologist to include giant cell arteritis (GCA, also known as temporal arteritis) in the differential diagnosis and to order an MRI, CT, and lab work.

When the patient saw the ophthalmologist about two weeks later, he reported a new symptom, a low-grade fever, with ongoing headache and diplopia. Five days after that—a full three weeks after the initial visit to the ophthalmologist—the patient lost vision in his left eye. An emergency room physician diagnosed giant cell arteritis and began intravenous steroid treatment, but the patient never regained vision in that eye. The malpractice lawsuit against the ophthalmologist settled for $85,000; we do not know the outcome of the suit against the neurologist.

Armed with hindsight bias, the classic signs and symptoms of giant cell arteritis jump out: older patient, vision changes, headache, jaw pain, and fever. It is hard to imagine how the definitive diagnosis and treatment were delayed for so long and easy to erroneously conclude that both physicians must have been incompetent. The claims investigation showed instead that these physicians had treated patients with giant cell arteritis, knew its signs and symptoms well, and understood that emergent treatment is needed to prevent imminent, bilateral vision loss. What, then, led these physicians astray?

Severe vision loss, costly claims

This issue of the Digest will report on a study of OMIC claims involving 18 patients diagnosed with GCA between 1993 and 2014. In 12 of the 18 cases (66%), no physician included GCA in the differential diagnosis. Four of these patients were seen only by an ophthalmologist; the rest were examined by an eye surgeon and one to three additional physicians. And although GCA was considered by the ophthalmologists in each of the remaining six cases, symptoms in five patients progressed when either the ophthalmologists or other physicians did not follow through to confirm the diagnosis and coordinate treatment. All 18 patients experienced severe vision loss, often bilaterally. OMIC had to settle twice as many of these claims as OMIC claims overall, and the mean and median payments were both considerably higher (see table 1).

TABLE 1A

 

 

 

 

 

 

 

The short window for diagnosis and treatment and the risk of severe bilateral vision loss make the high stakes of this relatively rare condition clear. This issue of the Digest will explore the reasons for these poor outcomes, the standard to which medical experts hold physicians who treat these patients, and the measures ophthalmologists can take to improve the likelihood of a correct and timely diagnosis.

Patients presenting with only visual problems

Giant cell arteritis, a systemic inflammation of the blood vessels that restricts blood flow causing organ and tissue damage, most commonly affects patients over the age of 50. In addition to the symptoms noted above and scalp tenderness, varied and non-specific constitutional symptoms, such as fatigue, malaise, and weight loss, may develop over time. It can be difficult to diagnose GCA when the only symptom is a change in vision. Four of the 18 patients presented this way. In two of these cases, defense experts supported the ophthalmologists’ care and the claims closed without payment, even though the insureds did not diagnose GCA or such diagnosis was delayed. In one case, a patient with dense cataracts that explained her vision loss was appropriately referred for work-up of a choroidal mass; the jury returned a defense verdict. In the second case that closed without a payment, a patient who presented with intermittent blurry vision was diagnosed with amaurosis fugax, a temporary loss of vision in one eye caused by a lack of blood flow to the retina. Because the patient was 79, the ophthalmologist ordered an erythrocyte sedimentation rate (ESR). When the result was normal at six, he repeated the test and got the same result. He diagnosed GCA six days later when the patient complained of a shade over the eye and developed a Marcus Gunn pupil and visual field deficit. OMIC declined the patient’s settlement demand and the case was ultimately dismissed. The two other cases where vision change was the only symptom were settled when OMIC could not find supportive defense experts. In one, the ophthalmologist noted papilledema in an 81-year-old who presented with sudden vision loss, but he did not work up its cause. The case settled for $275,000. In the other, the ophthalmologist was criticized for not clarifying the nature of the visual complaint. The 82-year-old patient had written on the history form that her vision “blacked out.” The surgeon did not read the form and documented only “blurry vision” and diagnosed her with visual migraine. The case settled for $350,000.

Problems eliciting a thorough and accurate history

Exploring the precise nature of the vision change would have helped another ophthalmologist entertain a GCA diagnosis. His patient complained of a headache for two days and a “curtain,” which he understood to be transparent. It was only during the investigation of the lawsuit that he learned the patient had experienced a “dark” curtain that caused frank vision loss. He felt, in retrospect, that the combination of vision loss and headache in an elderly patient should have alerted him to GCA and agreed to settle the claim for $100,000.

While it is important to get accurate information about the eye complaint, it is crucial to query older patients about constitutional symptoms. A careful review of signs, symptoms, and systems can help distinguish the few patients who could have GCA from the large number of older patients with eye problems seen daily in ophthalmic practices. Which symptoms did the patients in our study exhibit? Consistent with GCA’s usual appearance in patients over 50 years old, those in this study ranged from 62 to 86. As part of a claims investigation, defense attorneys obtain and review all of the patient’s medical records. These reviews revealed that 15 of the 18 patients (83%) were experiencing GCA symptoms other than vision changes at the time of their initial visit to the ophthalmologist. Of these 15 patients, 12 reported headaches and 7 of the 12 had additional symptoms (see table 2).

TABLE 2a

The ophthalmologists, however, failed to elicit the non-vision-related symptoms in 10 of the 15 patients (66%) who were having them. Defense experts opined that this inadequate history contributed to the delay in diagnosis and was below the standard of care. The ophthalmologist in the claim described in the beginning of this article learned only of the vision complaints and headache, while the neurologist, who saw the patient near the same time, elicited the duration of the headache and the existence of jaw pain. Ironically, the ophthalmologist testified in his deposition that he did not consider GCA in his differential diagnosis since the patient did not complain of jaw pain. He did not explain why he relied upon the patient to offer this information instead of asking for it.

Why is obtaining an accurate history so difficult? First, patients often report their history differently to each healthcare provider based upon the questions asked and the time spent gathering the information. Often it was other physicians who obtained a more thorough history, but in two of our claims, the ophthalmologists’ staff members obtained and documented the presence of GCA symptoms. Not only did the ophthalmologists not get the same information when questioning the patients a few minutes later, they also did not review the notes made by their staff members. This lapse was criticized by defense experts and contributed to the decision to settle these claims. Second, patients presenting with eye complaints often do not think that it is important or pertinent to tell their ophthalmologist about non-ophthalmic problems they are experiencing. More than in most diseases, however, prompt diagnosis of GCA depends upon the thoroughness and accuracy of the health history. In each of the 15 claims where patients had more than just visual symptoms, the plaintiff expert alleged that the diagnosis could have been made earlier if the ophthalmologist had obtained a more thorough history. Ophthalmologists examining older patients, especially those with vision changes and headache, need to take a more active role in obtaining the history. Dr. Ron Pelton, a practicing oculofacial surgeon who serves on OMIC’s claims and underwriting committees, has developed a GCA checklist to prompt ophthalmologists to ask key questions and document both positive and negative findings. It can be found at www.omic.com/giant-cell-arteritis-checklist/.

Missed opportunities

So what happened in the first case? While the ophthalmologist did not elicit a thorough history or include GCA in his differential diagnosis, the neurologist to whom he referred the patient did ask the appropriate questions. The combination of diplopia and pain in the temporal mandibular joint led the neurologist to a robust differential diagnosis, which included right fourth nerve palsy versus right inferior oblique paresis, brain stem ischemia, myasthenia gravis, and vasculitis. He appropriately ordered an MRI, CT scan, and laboratory work, including an ESR. About a week after he examined the patient, the neurologist realized that the lab had mistakenly not performed the ESR. He mailed the patient a prescription to have it done the next day but the patient never went. Six days later, the patient brought the results of the MRI, CT, and lab work (minus any ESR results) to his second visit with the ophthalmologist, who skimmed the report, which discussed the non-specific MRI and CT results and the normal lab results. He failed to notice that the lab had not performed the ESR. While he did see that the patient had been given a prescription to have the ESR repeated six days prior, he assumed the test had been done and was again normal. The ophthalmologist advised the patient to keep his follow-up appointment with the neurologist in four days time. Experts who reviewed the claim felt that four opportunities for an earlier diagnosis that would have preserved the vision had been lost: when the lab did not perform the first ESR ordered, when the patient did not go back to get the ESR lab test done, when the neurologist did not follow up to ensure it was done, and when the ophthalmologist failed to note the lack of ESR results. Had the ophthalmologist asked the patient, he would have learned that no ESR had been done. This information, combined with the new symptom of fever, could have prompted him to consider GCA and order a stat ESR.

Preventing vision loss

This constellation of incomplete history, poor coordination of care among physicians, and problems with patient adherence occurred in many of the claims, including the one in the Closed Claim Study. This article provides information on actions ophthalmologists can take, such as proactively obtaining a more thorough history, to improve the likelihood of including GCA in the differential diagnosis when older patients present with vision changes. The checklist created by Dr. Pelton can prompt such questions and help track the completion of key tests and consults. A robust appointment and test tracking system plays a pivotal role in preventing diagnostic error (see “Test Management System is Key to Prompt Diagnosis” and “Noncompliance” at www.omic.com for advice on how to implement one). The Hotline article in this issue provides recommendations on ways to improve communication with other physicians and your staff.

 

 

 

 

 

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